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Inderal is the brand name for propanolol, a prescription drug used to treat high blood pressure (hypertension).
It’s also used to treat severe chest pain ( angina ), migraines, thickened heart muscle (hypertrophic subaortic stenosis), tremors, a rare tumor called pheochromocytoma, and a movement disorder known as akathisia.
Off-label, Inderal is used to treat esophageal bleeding, aggressive behavior, and panic attacks.
Inderal is a beta blocker.
It works by changing the response to nerve impulses in the heart and other body parts, thus making the heart beat more slowly and reducing blood pressure.
As blood pressure lowers, the heart pumps more efficiently.
Sir James Black, who won the Nobel Prize in Medicine in 1988, developed propranolol in the 1960s.
The invention is widely viewed as one of the most important contributions to medicine and pharmacology in the 20 th century.
The Food and Drug Administration (FDA) approved Inderal, initially made by Wyeth, in 1967.
Currently, a number of companies make generic propranolol.
A long-acting form for once-a-day dosing has also been approved.
In 2006, the FDA issued a warning letter to Wyeth after receiving reports from consumers who said they found screws and washers inside the bottles of Inderal LA (a long-acting form of the drug).
The FDA cited the Wyeth plant for not following good manufacturing practices and the drug maker took corrective actions.
Inderal for Anxiety Inderal is prescribed “off-label” for panic attacks.
A study published in 1976 concluded that propranolol could help symptoms of anxiety.
However, a study published in 2013 described a case of an 11-year-old boy with bipolar -1 disorder and panic disorder who developed manic symptoms after taking propranolol.
Infusion of propranolol flattened action potential duration restitution, reduced wavebreaks and converted ventricular fibrillation to ventricular tachycardia.
Also, propranolol may order famvir online to stress echocardiography in for ischemia. Metabolism and Elimination The elimination half-life (T? beta) is between 2 and 5.5 hours. Zepro (Inderal Hydrochloride) is extensively metabolized with most metabolites appearing in the urine. Third, it is possible that other, non-genotype-related criteria might identify burn patients in the study population who would experience pain relief with propranolol treatment.
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