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Additional information about the drug Reglan

Reglan is the brand name of the drug metoclopramide, which is used to treat heartburn and ulcers in people with gastroesophageal reflux disease (GERD).
GERD is a digestive disorder that occurs when stomach acid flows back into the esophagus.
Reglan can also help people with diabetes who have a condition known as gastroparesis (poor emptying of the stomach).
It can also be used to treat nausea in certain patients and slowed stomach emptying in those who are recovering from surgery.
This medicine is typically used on a short-term basis (four to 12 weeks).
Reglan is in a class of drugs called prokinetic agents, which work by increasing muscle contractions in the upper digestive tract to speed up movement through the stomach and intestines.
The Food and Drug Administration (FDA) approved Reglan in 1985.
Reglan for Dogs Reglan may be used to prevent vomiting in dogs, especially chronic vomiting caused by kidney problems or vomiting after surgery.
It can also be used to treat symptoms of acid reflux in dogs.
You should talk to your veterinarian before using this medication for your pet.
Reglan and Tardive Dyskinesia The FDA requires that Reglan carry a black-box warning about the drug’s association with a serious (sometimes permanent) movement disorder known as tardive dyskinesia.
Taking Reglan may increase your risk of developing tardive dyskinesia.
Symptoms of this disorder include restlessness and uncontrollable muscle movements in the lips, tongue, eyes, face, arms, or legs.
The risk of developing tardive dyskinesia is higher in older adults, women, patients taking medicines for mental illness, and people with diabetes.
Your risk for this condition is also greater if you take Reglan for a longer period of time.
Your doctor will probably tell you not to take Reglan for longer than 12 weeks.
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  • However, the level of evidence regarding the benefits of metoclopramide for the management of gastroparesis is weak, and given the risk for serious adverse effects (extrapyramidal signs such as acute dystonic reactions, drug-induced parkinsonism, akathisia, and tardive dyskinesia), its use in the treatment of gastroparesis beyond 5 days is no longer recommended by the FDA or the European Medicines Agency.
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