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Additional information about the drug Protonix

Protonix
Protonix is a prescription medication used to treat gastroesophageal reflux disease and Zollinger-Ellison Syndrome. Protonix belongs to a group of drugs called proton pump inhibitors. These work by decreasing the amount of acid made in the stomach.
This medication comes in a delayed release tablet and oral (by mouth) suspension form. It is usually taken once or twice daily, with or without food.
This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional.
Common side effects of pantoprazole include headache, diarrhea, and nausea.
CYP2C19 is an enzyme in the blood that is responsible for breaking down pantoprazole and other drugs in the body. Some patients have less of this protein in their bodies, affecting how much of the drug gets eliminated. Levels of CYP2C19 can vary greatly between individuals, and those having less of this protein are known as “poor metabolizers.” 
CYP2C19 testing is done to determine whether you are a poor metabolizer. If you are a poor metabolizer, the levels of pantoprazole in your blood can become too high. As a result you may be at an increased risk of having more side effects from pantoprazole. 
Your doctor may adjust your dose of pantoprazole if you are a poor metabolizer.
Protonix is a prescription medication used for:
​This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Protonix may be found in some form under the following brand names:
Protonix is part of the drug class:
Protonix can cause serious side effects including:
Your doctor may stop pantoprazole if these symptoms happen.
The most common side effects with pantoprazole in adults include:
The most common side effects with pantoprazole in children include:
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  • In patients with severe renal impairment, pharmacokinetic parameters for Protonix were similar to those of healthy subjects.However, the study only looked at the association between time spent sitting and early death risk, and did not try to prove a causeandeffect relationship.
  • There have been reports of increased International Normalized Ratio (INR) and prothrombin time in patients receiving other proton pump inhibitors (PPIs) (including esomeprazole, lansoprazole, rabeprazole, and pantoprazole and warfarin concomitantly.
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