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Protonix is a prescription medication used to treat gastroesophageal reflux disease and Zollinger-Ellison Syndrome. Protonix belongs to a group of drugs called proton pump inhibitors. These work by decreasing the amount of acid made in the stomach.
This medication comes in a delayed release tablet and oral (by mouth) suspension form. It is usually taken once or twice daily, with or without food.
This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional.
Common side effects of pantoprazole include headache, diarrhea, and nausea.
CYP2C19 is an enzyme in the blood that is responsible for breaking down pantoprazole and other drugs in the body. Some patients have less of this protein in their bodies, affecting how much of the drug gets eliminated. Levels of CYP2C19 can vary greatly between individuals, and those having less of this protein are known as “poor metabolizers.”
CYP2C19 testing is done to determine whether you are a poor metabolizer. If you are a poor metabolizer, the levels of pantoprazole in your blood can become too high. As a result you may be at an increased risk of having more side effects from pantoprazole.
Your doctor may adjust your dose of pantoprazole if you are a poor metabolizer.
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