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Aricept, which is sold under the brand name Aricept, is a cholinesterase inhibitor (an enzyme blocker) used to treat mild, moderate, or severe dementia in people who have Alzheimer’s disease.
It improves mental functions (including attention, memory, and the ability to interact and speak with others) by preventing the naturally occurring neurotransmitters in the brain from breaking down.
It will not cure Alzheimer’s or prevent the loss of mental abilities in the future.
Aricept was approved by the Food and Drug Administration (FDA) in 1996 to treat mild to moderate Alzheimer’s.
Currently, donepezil is the world’s best-selling Alzheimer’s drug.
In 2006, Aricept was approved to treat severe dementia in people with Alzheimer’s.
The first generic formulation became available in 2010.
Aricept has also been tested in patients with schizophrenia, attention deficit disorder, and mild cognitive impairment.
A 2001 study shows donepezil improves the speech of autistic children.
Aricept Warnings Aricept must be taken as prescribed, even if you feel good, to be effective.
If you experience sleep problems, your doctor may switch you to a morning dose.
Before taking donepezil, consult with your doctor if you are pregnant or breastfeeding, or if you are planning to have surgery, including dental surgery.
Aricept should be used with caution by patients who also experience cardiac disease, asthma, severe cardiac arrhythmias, and chronic obstructive pulmonary disease (COPD), so consult with your doctor before using.
Always tell your doctor if your symptoms worsen.
BasicDescription Back to Top Aricept Side Effects Less serious side effects include: Loss of appetite Weight loss Nausea Vomiting Diarrhea Frequent urination Muscle cramps, painful and swollen joints Excessive tiredness Difficulty falling asleep Headache, nervousness, dizziness Depression, mood swings Vivid dreams More serious side effects may demand immediate emergency medical attention and include: Chest pain Difficulty with urination Swelling of the tongue, throat, or face Severe anemia Slow heartbeat Breathing problems Fainting Worsening stomach pain Black or bloody stools Bloody vomit Seizures Fever Back to Top Aricept Interactions Drugs with anti-cholinergic properties that counteract donepezil and should be avoided include: Bentropine ( Cogentin ) Atropine (Atropine Sulfate) Trihexyphenidyl (Artane) The following medications, which increase enzymes in the liver, may reduce the effect of donepezil: Phenobarbital (Luminal) Phenytoin (Dilantin) Rifampin (Rifadin) Carbamazepine (Tegretol) Dexamethasone (Decadron) There are other medications, both prescription and over-the-counter (OTC), that interact with donepezil.
It’s important to tell your doctor all of the medications you are taking.
Wilkinson D, Doody R, Helme R, Taubman K, Mintzer J, Kertesz A, Pratt RD; Aricept 308 Study Group.
Syncopal episodes have been reported in association with the use of donepezil hydrochloride. Therefore, patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs).However, seizure activity also may be a manifestation of Alzheimer’s disease. Aricept hydrochloride tablets have been administered to over 1,700 individuals during clinical trials worldwide. It sucks by flunking a donepezil that is brandnamed for the hiv arteries to multiply. However, we did see a difference between headline and title references to pharmaceutical use as well as to the potential medical use of donepezil (i.e., for memory restoration).
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