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Levothyroxine is a prescription medication used to treat underactive thyroid ( hypothyroidism ) and other thyroid problems. Levothroxine is a synthetic thyroid hormone, which replaces the body’s reduced levels of natural thyroid hormone.
This medication comes in tablet form and is taken once in the morning on an empty stomach, with a glass of water.
Common side effects of levothyroxine include tremors, change in appetite, and irregular heartbeats.
Levothyroxine, a synthetic thyroid hormone, is a prescription medication used as a replacement or supplemental therapy in hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. This medication is also used to treat nodules and goiters, as well as some types of thyroid cancer.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Levothyroxine may be found in some form under the following brand names:
Levothyroxine is part of the drug class:
Too much levothyroxine can cause symptoms of hyperthyroidism. If you experience the following symptoms, call your doctor right away as your dosage may need to be reduced:
Levothyroxine can cause allergic reactions. Symptoms include:
Call your doctor right away if you experience symptoms of allergic reaction.
This is not a complete list of levothyroxine side effects. Ask your doctor or pharmacist for more information.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Many medicines affect the absorption and metabolism of levothyroxine and may change the way your body responds to levothyroxine. Additionally, levothyroxine has effects on the way your body responds to other medicines. The following medicines may interact with levothyroxine:
This is not a complete list of levothyroxine drug interactions. Ask your doctor or pharmacist for more information.
You should not take levothyroxine if you:
Use levothyroxine only as prescribed by your physician. Do not discontinue or change the amount you take or how often you take it, unless directed to do so by your physician.
It may take several weeks before you notice an improvement in your symptoms.
Tell your doctor if you become pregnant while taking levothyroxine. It is likely that your dose of levothyroxine will need to be increased while you are pregnant.
Notify your doctor or dentist that you are taking this medicine prior to any surgery.
Partial hair loss may occur rarely during the first few months of levothyroxine therapy, but this is usually temporary.
Levothyroxine should not be used as a weight loss medication in people without hypothyroidism.
Iron and calcium supplements and antacids can decrease the absorption of levothyroxine. Therefore, levothyroxine should not be administered within 4 hrs of these products.
Levothyroxine may increase your risk of developing osteoporosis, especially if your levothyroxine dose is too high.
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of levothyroxine there are no specific foods that you must exclude from your diet when receiving levothyroxine.
Before taking levothyroxine tell your doctor:
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Tell your doctor if you are pregnant or plan to become pregnant. Studies in women taking levothyroxine during pregnancy have shown it is safe for use during pregnancy. It does not appear to cause harm to the unborn baby. In fact, it is important to treat hypothyroidism (underactive thyroid) during pregnancy, as undertreatment can be dangerous. Pregnant women often require higher doses of levothyroxine.
Tell your doctor if you are breastfeeding or plan to breastfeed. Small amounts of levothyroxine are excreted in human breastmilk, just as natural thyroid hormone passes through breast milk. However, women who don’t have enough thyroid hormone may not be capable of lactation (secretion or formation of milk).
Levothyroxine is a tablet that is taken by mouth, usually once a day. It should be taken with a full glass of water. Take levothyroxine in the morning on an empty stomach, at least one-half hour to one hour before eating any food. Iron and calcium supplements and antacids can decrease the absorption of levothyroxine tablets. Take these products at least 4 hours before or 4 hours after you take levothyroxine.
If needed, levothyroxine tablets can be crushed and mixed in 1 to 2 teaspoons of plain water. This mixture must be taken right away.
If you forget a dose of levothyroxine, take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose. Do not take a double dose of this medication.
Note: if you are prescribed levothyroxine in capsule form, you must swallow them whole. Never crush these capsules.
Dosing of levothyroxine must be individualized. Your doctor will determine the best levothyroxine dose for you, which will likely be carefully and slowly adjusted. Regular blood tests will be required to monitor your progress. Follow the directions on your prescription label carefully. Do not take more or less than prescribed. It may take several weeks before you begin to notice a change in your symptoms. Do not stop taking levothyroxine without talking to your doctor.
If you take too much levothyroxine, call your local Poison Control Center or seek emergency medical attention right away.
Store levothyroxine away from heat, moisture, and light.
Keep this and all medicines out of the reach of children.
WARNING: Thyroid hormones, including Levothyroxine Sodium Tablets, USP, either alone or with other therapeutic agents, should not be used for the treatment of obesity for weight loss. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.

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