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Etodolac is a non-steroidal anti-inflammatory drug ( NSAID ) used to treat mild to moderate pain, and to relieve symptoms of arthritis ( osteoarthritis and rheumatoid arthritis ), such as inflammation, swelling, stiffness, and joint pain.
Lodine, the brand-name formulation of the drug, has been discontinued in the United States, and only the generic form of etodolac is available.
Etodolac works by reducing the levels of hormones that cause inflammation and pain in the body.
Etodolac may also be used for other purposes.
Some examples of the off-label uses of this drug include the relief of: Fibromyalgia symptoms Gout symptoms Symptoms of systemic lupus erythematosus (SLE or lupus) Pain or inflammation caused by other conditions, such as back pain, knee pain, or foot pain.
Etodolac Warnings This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke.
This risk will increase the longer you use etodolac.
Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).
Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.
This medicine can also increase your risk of stomach or intestinal problems, including bleeding or perforation (formation of a hole).
These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking etodolac.
Older adults may have an even greater risk of these serious gastrointestinal side effects.
Call your doctor at once if you have symptoms of bleeding in your stomach or intestines.
This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist.
Many medicines available over the counter contain aspirin or other medicines similar to etodolac, such as ibuprofen ( Advil, Motrin, Mydol), ketoprofen (Actron, Orudis, Oruvail), or naproxen (Aleve).
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