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Store clindamycin at room temperature. Clindamycin
Clindamycin ( topical ) is a prescription medication used to treat acne. Clindamycin ( vaginal ) is a prescription medication used to treat bacterial infections of the vagina, a female reproductive organ. Clindamycin ( oral and injection ) is a prescription medication used to treat bacterial infections of the skin, airways, blood, joints, bones, female reproductive organs, and internal organs.
Clindamycin ( topical, vaginal, oral, and injection ) belongs to a group of drugs called lincosamide antibiotics, which slow or stop the growth of bacteria.
Clindamycin ( topical ) comes in topical foam, solution, lotion, gel, and medicated swab forms. These dosage forms are applied to the skin with acne once or twice a day. Clindamycin ( vaginal ) comes in vaginal suppository and cream forms. These dosage forms are typically used once a day at bedtime. Clindamycin ( oral ) comes in capsule and solution forms, and is taken by mouth up to 4 times a day with or without food.  Clindamycin ( injection ) is given into the vein (IV) or into the muscle (IM) by a healthcare professional when needed.
Common side effects of clindamycin ( topical ) include dry, peeling, and irritated skin. Common side effects of clindamycin ( vaginal ) include vaginal irritation, swelling, and discharge. Common side effects of clindamycin ( oral and injection ) include nausea, vomiting, constipation, and rash.
These medications may be prescribed for other uses. Ask your doctor or pharmacist for more information.  
Serious side effects have been reported with clindamycin. See “Drug Precautions” section.
Common side effects of clindamycin ( topical ) include:
Common side effects of clindamycin ( vaginal ) include:
Common side effects of clindamycin ( oral and injection ) include:
This is not a complete list of these medications’ side effects. Ask your doctor or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.  
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
Clindamycin ( topical, vaginal, oral, and injection )
This is not a complete list of these medications’ drug interactions. Ask your doctor or pharmacist for more information.  
Serious side effects have been reported with clindamycin ( topical, vaginal, oral, and injection ) including:
Do not take clindamycin ( topical, vaginal, oral, and injection ) if you:
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case clindamycin, there are no specific foods that you must exclude from your diet when receiving clindamycin.
Before taking clindamycin, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.  
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories – A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Clindamycin ( topical, vaginal, oral, and injection ) falls into category B. Studies in animals have failed to demonstrate a risk to the unborn baby and there are no well-controlled studies in pregnant women.
Tell your doctor if you are breastfeeding or plan to breastfeed.
Clindamycin ( topical, vaginal, oral, and injection ) has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from this medication, a choice should be made whether to stop nursing or to stop use of clindamycin. Determining the importance of the drug to the mother should be considered.  
If you miss a dose of clindamycin ( topical, vaginal, or oral ), take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of clindamycin at the same time.
Take clindamycin exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
If you take too much clindamycin, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
Clindamycin ( topical ) is available in:
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Inactive ingredients: varies by manufacturers and dosage forms
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Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the INDICATIONS AND USAGE section. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections. C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.

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