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Zyloprim is the brand name of the drug allopurinol, which is used to treat gout, high levels of uric acid in the body (often caused by certain cancers and cancer treatments), and kidney stones.
The medication may also be used to treat seizures, infections, and pain caused by pancreas disease.
It is sometimes used to improve survival after bypass surgery, prevent rejection of kidney transplants, or reduce ulcer relapses.
Zyloprim is a type of medication called a xanthine oxidase inhibitor.
It works by reducing the production of uric acid in the body.
It comes in the form of an oral tablet.
Zyloprim Warnings Your doctor will likely start you on a low dose of allopurinol and gradually increase it.
It may take several months before you feel the full benefits of this medicine.
Zyloprim may increase the number of gout attacks you experience during the first few months you take it, but it will eventually prevent the attacks from occurring.
You should tell your doctor if you have any of the following conditions before taking allopurinol: Liver disease Kidney disease Diabetes Congestive heart failure High blood pressure Are pregnant or breastfeeding Are receiving chemotherapy drugs Zyloprim can decrease the number of blood cells in your body that make blood clot and that help you fight infections, which can make it easier for you to bleed from an injury or get sick when exposed to others who are ill.
You should avoid being around people who are sick or have infections while taking this medicine.
See your doctor regularly while taking this drug.
Your blood may need to be tested to check your body’s reaction to the medication.
BasicDescription Back to Top Zyloprim Side Effects Some less serious side effects of allopurinol may include: Vomiting Diarrhea Drowsiness Headache Muscle pain Changes in sense or taste Serious Side Effects of Zyloprim Call your doctor immediately if you experience any of the following serious side effects: Fever, sore throat, and headache with a severe blistering, peeling and red skin rash Any sign of skin rash, no matter how mild Nausea, upper stomach pain, itching, loss of appetite, weight loss, dark urine, clay-colored stools, jaundice Pain or bleeding when urinating Urinating less frequently or not at all Joint pain or flu symptoms Easy bruising, unusual bleeding, or purple or red pinpoint spots under the skin Severe tingling, numbness, pain, or muscle weakness Back to Top Zyloprim Interactions Since other medications may interact with allopurinol, tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking, especially: Azathioprine (Imuran) Chlorpropamide (Diabinese) Cyclosporine (Gengraf, Sandimmune, Neoral) Mercaptopurine (Purinethol) Antibiotics such as ampicillin (Principen, Omnipen, others) or amoxicillin (Amoxil, Augmentin, Trimox, Wymox) Blood thinners such as warfarin ( Coumadin ) Diuretics (water pills) Should I Avoid Any Food, Drink or Activity While Taking Zyloprim? Avoid drinking alcohol while taking allopurinol, as it may make your condition worse.
Zyloprim may impair your thinking or reaction time, so you should be especially careful when driving or performing any activity that requires you to be alert.
Your doctor may advise you to follow a special diet to help treat your condition.
This nonmetastatic cholestasis has been described in non-Hodgkin’s lymphoma, prostate cancer, and renal cell carcinoma. 35 – 38 Granuloma formation in the liver occurs in various disorders, including systemic infections from bacteria, viruses, fungi, rickettsia, spirochetes, and parasites; drugs and chemicals; immune-mediated diseases, such as sarcoidosis and primary biliary cirrhosis; and neoplasms, such as Hodgkin’s disease ( Box 3 ). 39, 40 The list of commonly used drugs that result in hepatic granulomas is extensive; it includes allopurinol, quinidine, sulfonamides, and sulfonylureas.
Therefore, coagulation indices should be monitored to maintain the desired anticoagulant effects. This interaction may be expected with all competitive neuromuscular blockers. Discontinuation of methylprednisolone treatment can lead to raised salicylate serum levels, which could lead to an increased risk of salicylate toxicity. Drugs that are physically incompatible in solution with methylprednisolone sodium succinate include allopurinol sodium, doxapram hydrochloride, tigecycline, diltiazem hydrochloride, calcium gluconate, vecuronium bromide, rocuronium bromide, cisatracurium besylate, glycopyrrolate and propofol. (See section 6.2 for additional information.) There is no evidence that corticosteroids result in an increased incidence of congenital abnormalities, such as cleft palate in man, however, when administered for long periods or repeatedly during pregnancy, corticosteroids may increase the risk of intra-uterine growth retardation. They hear it all the time. ?? Gail Reply August 18, 2018 Jayne, Zyloprim is an excellent medication, with few side effects, and good availability but it is not true that if you are taking it you will never have another attack. So she rolled her eyes and gave me indomethacin for the acute pain relief, a scrip I never filled, after doing some reading, for allopurinol as a preventative, a recommendation of abstention from alcohol (r-i-i-i-g-h-t, doc.And moderation, but not fanaticism, with both diet and beer consumption.
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