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Additional information about the drug Mestinon

Mestinon is a medication used to treat myasthenia gravis.
Common side effects include nausea, diarrhea, frequent urination, and abdominal pain.
Mestinon was patented in 1945 and came into medical use in 1955.
Contents
1 Medical uses
2 Contraindications
3 Side effects
4 Mechanism of action
5 Names
6 References
Medical uses
Mestinon is used to treat muscle weakness in people with myasthenia gravis or forms of congenital myasthenic syndrome and to combat the effects of curariform drug toxicity. Mestinon bromide has been FDA approved for military use during combat situations as an agent to be given prior to exposure to the nerve agent Soman in order to increase survival. Used in particular during the first Gulf War, pyridostigmine bromide has been implicated as a causal factor in Gulf War syndrome.
Mestinon sometimes is used to treat orthostatic hypotension.
It is also being prescribed ‘off-label’ for the postural tachycardia syndrome as well as complications resulting from Ehlers–Danlos syndrome.
Contraindications
Mestinon bromide is contraindicated in cases of mechanical intestinal or urinary obstruction and should be used with caution in patients with bronchial asthma.
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  • Oral supplementation may also help; however order 60mg pyridostigmine free shipping, because of the severity of this condition an infusion may be more appropriate for many patients, since this can provide immediate relief.
  • We report a double-blind, randomized, 4-way cross-over study of pyridostigmine in the treatment of neurogenic OH.
  • Does mestinon (pyridostigmine) increase blood pressure?
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