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Avanafil is a prescription medication used to treat erectile dysfunction in men.
Avanafil belongs to a group of drugs called phosphodiesterase (PDE) inhibitors. These work by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection.
This medication comes in tablet form and is taken typically once a day, on an as needed basis, approximately 30 minutes before sexual activity. Avanafil can be taken with or without food.
Common side effects of avanafil include headache, flushing, and back pain.
Avanafil is a prescription medication used to treat erectile dysfunction in men.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Avanafil may be found in some form under the following brand names:
Avanafil is part of the drug class:
Serious side effects have been reported with avanafil. See the “Avanafil Precautions” section.
Common side effects of avanafil include the following:
This is not a complete list of avanafil side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
This is not a complete list of avanafil drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with avanafil including the following:
Talk to your doctor about the safe use of alcoholic beverages during your treatment with avanafil. If you drink a large amount of alcohol (more than three glasses of wine or three shots of whiskey) while you are taking avanafil you are more likely to experience certain side effects of avanafil such as dizziness, headache, fast heartbeat, and low blood pressure.
Grapefruit and grapefruit juice may interact with avanafil and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
Before taking avanafil, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories – A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Avanafil falls into category C. Avanafil is not indicated for use in women. There are no adequate and well-controlled studies of avanafil in pregnant women.
Tell your doctor if you are breastfeeding or plan to breastfeed.
It is not known if avanafil crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using avanafil.
Take avanafil exactly as prescribed. Your healthcare provider will tell you how much avanafil to take and when to take it.
Avanafil comes in tablet form and is taken typically once a day, on an as needed basis. Avanafil can be taken with or without food.
Take avanafil about 30 minutes before sexual activity. Some men may achieve an erection in approximately 15 minutes, and therefore, may be taken 15 minutes before sexual activity.
Do not take more avanafil than 1 time a day.
Do not drink too much alcohol when taking avanafil (for example, 3 glasses of wine, or 3 shots of whiskey). Drinking too much alcohol when taking avanafil can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.
Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dose your doctor recommends may be based on the following:
The dose range of Stendra (avanafil) is 50 mg-200 mg. For most patients, the starting dose is 100 mg taken approximately 30 minutes before sexual activity, on an as needed basis.
You should take the lowest dose of avanafil that works for you. You and your healthcare provider should decide on the lowest dose of avanafil that works for you.
Your healthcare provider may change your dose if needed and may be based on efficacy and tolerability.
If you take too much avanafil, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

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